Retrieving articles on "etiology" from MEDLINE


Here, we tackle the retrieval of article citations on etiology of a disease - especially if there is a factor of "harm" ie., diseases that strike because of environmental factors, or by adverse effects of therapeutic drugs, etc. What we really need to retrieve is evidence that a disease IS caused by a specific factor or a group of factors.

Let us consider an example from the dental field. There has been a controversy about the use of fluorides in toothpastes, and also addition of fluorides in water - to the effect of whether these measures eventually cause fluorosis, and if so what levels of fluorides are safe to use for therapeutic reasons.

The boolean combination you'd use is:
1. fluorides/adverse effects OR fluorides/toxicity OR fluorides/poisoning
2. fluorosis/etiology OR fluorosis/chemically induced OR fluorosis/epidemiology


Modality of search

Click on Preview/Index, select MeSH terms from the dropdown, type in fluorides in the search box, and then click on Index. From the results, you'd choose fluorides/adverse effects, fluorides/poisoning and fluorides/toxicity.(Keep the control key pressed, as you select these options). Click on AND.

A search strategy:
("fluorides/adverse effects"[MeSH Terms] OR "fluorides/poisoning"[MeSH Terms] OR "fluorides/toxicity"[MeSH Terms]) will appear in the search box at the top.

Next Click on Preview/Index, select MeSH terms from the dropdown, type in fluorosis in the search box, and then click on Index. From the results, you'd choose fluorosis/etiology, fluorosis/chemically inducedand fluorosis/epidemiology.(Keep the control key pressed, as you select these options). Click on AND.

A search strategy:
("fluorides/adverse effects"[MeSH Terms] OR "fluorides/poisoning"[MeSH Terms] OR "fluorides/toxicity"[MeSH Terms]) OR ("fluorosis, dental/chemically induced"[MeSH Terms] OR "fluorosis, dental/epidemiology"[MeSH Terms] OR "fluorosis, dental/etiology"[MeSH Terms]) will appear in the search box at the top. Click on "Go". You get 2199 citations.

This can be further refined by adding MeSH terms "risk factors" and "cohort studies" with the above while searching. You then get fourteen focused citations.


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